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Studio recente sull'efficacia di finasteride...


Dep

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E' uno studio recente fatto nel novembre del 2001 in Svizzera.

Da notare che la durata dello studio è di soli 6 mesi(dopo 12 mesi i risultati sarebbero stati molto probabilmente migliori) e che viene considerata sia la ricrescita del vertex sia quella della regione frontale.

 

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Photographic documentation of the effectiveness of 1 mg. oral

finasteride in treatment of androgenic alopecia in the man in routine

general practice in Switzerland.

 

Schweiz Rundsch Med Prax 2001 Nov 29;90(48):2087-93.

 

A 6-month, prospective, open, multicenter cohort study in 265 men with

male pattern hair loss treated with oral finasteride 1 mg/day

(Propecia) was conducted in the office of 52 Swiss dermatologists. The

patient's head was placed in a stereotactic device, and Polaroid

photographs were taken of the vertex and frontal areas. Endpoints used

to determine treatment efficacy were patient self-assessment,

investigator clinical assessment, and blinded assessment of the serial

Polaroid photographs by a panel of 2 experienced dermatologists.

Significant improvements were stated on the photographs by both

clinical investigators and the blinded expert panel: 54% of patients

showed improvement of hair growth at 6 months of treatment in the

vertex region, and 48.7% in the frontal area. No progression of hair

loss was found in an additional 38% (vertex) and 47% (frontal region),

respectively. Clinical investigator and expert assessment yielded

comparable results. Independently, patient self-assessment and

investigator clinical assessment confirmed the progress. Propecia was

well-tolerated, and no significant safety concerns were identified

during the study. The photographic method was well accepted by the

physicians. The office-based Polaroid photographic system allowed

reliable assessment of change during treatment of male pattern hair

loss with Propecia. The data generated in this manner corresponded to

the antecedent results of the multicenter, placebo-controlled studies

with oral finasteride.

 

Publication Types:

Clinical Trial

Clinical Trial, Phase IV

Multicenter Study

 

PMID: 11770252 [PubMed - indexed for MEDLINE]

 

P.S.=Please note that the key

metric used here was photographs of the "vertex and frontal areas",

and not hair counts in a small circle. Patients also rated their hair

status.

 

-Dep-

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